Atoh7 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:175804 Brzezinski JA 4th, et al., Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina. Development. 2011 Aug;138(16):3519-31
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:7855852
Gene symbol:	Atoh7
Gene name:	atonal bHLH transcription factor 7

Reporter:	Cre
Antibody:	anti-cre (Millipore; MAB3120)

Results

5B ©

5C ©

5D ©

Specimen 5B/C/D: embryonic day 13.5; Ascl1^tm1Reed/Ascl1⁺, Atoh7^tm3(cre)Gan/Atoh7⁺ (more

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Note: Triple labeled: white - Atoh7 reporter; green - Ascl1 reporter (assay MGI:7855848); red - Pou4f1 (assay MGI:7855853) and Pou4f2 (assay MGI:7856524) (assay MGI:7855853) and Pou4f3 (assay MGI:7856525).

Structure	Level	Pattern	Image	Note
TS21: retina	Present		5C , 5D , 5B	The central retinas had many cells that co-expressed Ascl1.

5F ©

5G ©

5H ©

Specimen 5F/G/H: embryonic day 13.5; Ascl1^tm1Reed/Ascl1⁺, Atoh7^tm3(cre)Gan/Atoh7⁺ (more

Structure	Level	Pattern	Image	Note
TS21: retina	Present		5G , 5H , 5F	In peripheral retinas, only one cell coexpressed Ascl1 and Brn3/Pou4f1/2/3.

S7B ©

S7C ©

S7D ©

Specimen S7B/C/D: embryonic day 18.5; Ascl1^tm1Reed/Ascl1⁺, Atoh7^tm3(cre)Gan/Atoh7⁺ (more

Structure	Level	Pattern	Image	Note
TS26: retina	Present		S7B , S7D , S7C	Few positive cells co-expressed Brn3/Pou4f1/2/3. Many cells co-expressed Ascl1-GFP.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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