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Gene Expression Data
Assay Details
Assay
Reference: J:294282 Li L, et al., The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855683
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Results
Specimen 1E Ctip2 Control: postnatal day 3; Tg(Dach1-cre)1Krs/0 (more )
Structure Cell Type Level Pattern Image Note
TS27: neocortex pyramidal neuron Present Regionally restricted 1E Ctip2 Control Expression in deep layer (layer V) projection neurons.
Specimen 1E Ctip2 cKO: postnatal day 3; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: neocortex Weak Regionally restricted 1E Ctip2 cKO Expression reduced in deep layer cortex.
Specimen 1F Ctip2 Control: postnatal day 3; Tg(Dach1-cre)1Krs/0 (more )
Note: Triple labeled: green - Bcl11b; gray - Cux1 (assay MGI:7855681); red - Tle4 (assay MGI:7855684).
Structure Cell Type Level Pattern Image Note
TS27: neocortex pyramidal neuron Present Regionally restricted 1F Control Expression in deep layer (layer V) projection neurons.
Specimen 1F Ctip2 cKO: postnatal day 3; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant. Triple labeled: green - Bcl11b; gray - Cux1 (assay MGI:7855681); red - Tle4 (assay MGI:7855684).
Structure Level Pattern Image Note
TS27: neocortex Weak Regionally restricted 1F cKO , 1F cKO inset Expression reduced in deep layer cortex.
Specimen 2A Ctip2 Control: postnatal day 3; Tg(Dach1-cre)1Krs/0 (more )
Note: Double labeled: green - Bcl11b; red - EdU.
Structure Level Pattern Image Note
TS27: neocortex Present 2A Ctip2 Control
Specimen 2A Ctip2 cKO: postnatal day 3; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant. Double labeled: green - Bcl11b; red - EdU.
Structure Level Pattern Image Note
TS27: neocortex Present 2A Ctip2 cKO
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory