Ash2ltm1.1Bcgen
Targeted Allele Detail
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Symbol: |
Ash2ltm1.1Bcgen |
Name: |
ASH2 like histone lysine methyltransferase complex subunit; targeted mutation 1.1, Biocytogen LLC |
MGI ID: |
MGI:7539520 |
Synonyms: |
Ash2lfl |
Gene: |
Ash2l Location: Chr8:26306028-26337722 bp, - strand Genetic Position: Chr8, 14.17 cM, cytoband A3
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Alliance: |
Ash2ltm1.1Bcgen page
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Germline Transmission: |
Earliest citation of germline transmission:
J:294282
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The targeting construct instructed a loxP site upstream of exon 4 and an FRT-flanked neomycin resistance cassette with a 3' loxP site downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exons 4 and 5 floxed.
(J:294282)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ash2l Mutation: |
43 strains or lines available
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Original: |
J:294282 Li L, et al., The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
All: |
2 reference(s) |
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