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Gene Expression Data
Assay Details
Assay
Reference: J:238086 Kusano R, et al., Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7840309
Gene symbol: Mbp
Gene name: myelin basic protein
Antibody: anti-MBP
Results
Specimen 3C wt/wt: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: anterior commissure Present 3C wt/wt
TS28: cerebellum Present 3C wt/wt
TS28: corpus callosum Present 3C wt/wt
TS28: corpus striatum Present 3C wt/wt
TS28: medulla oblongata Present 3C wt/wt
Specimen 3C delta/delta: postnatal day 28; Ppm1ltm1Tkoba/Ppm1ltm1Tkoba (more )
Structure Level Pattern Image Note
TS28: anterior commissure Weak 3C delta/delta In this mutant the number of positive dense fiber bundles was reduced compared to wildtype.
TS28: corpus callosum Weak 3C delta/delta In this mutant the number of positive dense fiber bundles was reduced compared to wildtype.
TS28: corpus striatum Weak 3C delta/delta In this mutant the number of positive dense fiber bundles was reduced compared to wildtype.
TS28: cerebellum Present 3C delta/delta Expression in this mutant is he same as in wild-type.
TS28: medulla oblongata Present 3C delta/delta Expression in this mutant is he same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory