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Gene Expression Data
Assay Details
Assay
Reference: J:214086 Parthasarathy S, et al., Ntf3 acts downstream of Sip1 in cortical postmitotic neurons to control progenitor cell fate through feedback signaling. Development. 2014 Sep;141(17):3324-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7840100
Gene symbol: Sox5
Gene name: SRY (sex determining region Y)-box 5
Antibody: anti-Sox5 (sc-17329)
Detection system: Secondary antibody
Results
Specimen 4C WT: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 4C WT Expression is in layer VI.

Specimen 4C Ntf3-/-: embryonic day 18.5; Ntf3tm1Jae/Ntf3tm1Jae (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present 4C Ntf3-/- The number of positive cells had increased in this mutant compared to wild-type.

Specimen 4C Sip1fl/fl;NexCre: embryonic day 18.5; Neurod6tm1(cre)Kan/Neurod6+, Zeb2tm1.1Yhi/Zeb2tm1.1Yhi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present 4C Sip1fl/fl;NexCre Expression in this mutant is the same as in wild-type.

Specimen 4C Sip1- Ntf3 DKO: embryonic day 18.5; Neurod6tm1(cre)Kan/Neurod6+, Ntf3tm1Jae/Ntf3tm1Jae, Zeb2tm1.1Yhi/Zeb2tm1.1Yhi (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present 4C Sip1- Ntf3 DKO Expression in this mutant is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory