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Gene Expression Data
Assay Details
Assay
Reference: J:38838 Muller U, et al., Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis. Cell. 1997 Mar 7;88(5):603-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736534
Gene symbol: Itga8
Gene name: integrin alpha 8
Antibody: anti-alpha8 extracellular
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: mesenchyme of metanephros Strong Regionally restricted 2A Expression is in mesenchymal cells surrounding the Wolffian duct, and is high at the interface between the duct epithelium and the surrounding mesenchymal cells. Expression is throughout the mesenchyme of the nephrogenic cord.
Specimen 2B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: mesenchyme of metanephros Strong Regionally restricted 2B Expression is in mesenchymal cells above the tip of the growing ureteric bud and surrounding the ureteric bud.
Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Strong 2C Expression is in the condensing mesenchyme surrounding the tips of the branching ureter.
Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Strong Regionally restricted 2D Expression is in mesenchymal cells bordering on the ureteric epithelium.
Specimen 2E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Strong Regionally restricted 2E Expression is in the condensing mesenchyme surrounding the tips of the branching ureter. Expression is in mesenchymal cells bordering on the ureteric epithelium.
Specimen 2F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pretubular aggregate Strong 2F
TS21: s-shaped body Absent 2F
Specimen 2G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: comma-shaped body Absent 2G
Specimen 2H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mesenchyme of metanephros Strong Regionally restricted 2H Expression is in the outer layer of the kidney on condensing mesenchymal cells.
TS24: maturing glomerular tuft Absent 2H
Specimen 3D +/+ ex: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lung Present 3D +/+ ex
Specimen 3D -/- ex: postnatal day 0; Itga8tm1Lfr/Itga8tm1Lfr (more )
Structure Level Pattern Image Note
TS27: lung Absent 3D -/- ex
Specimen 7E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: urothelium of ureter Present Regionally restricted 7E Expression is on the surface of the branching ureteric epithelium.
Specimen 7G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: urothelium of ureter Present Regionally restricted 7G Expression is on the surface of the branching ureteric epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory