Arl13b Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:353362 Walker MF, et al., GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade. PLoS Biol. 2024 Aug;22(8):e3002685
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7734749
Gene symbol:	Arl13b
Gene name:	ADP-ribosylation factor-like 13B

Antibody:	anti-ARL13B [N295B/66] ab136648
Detection system:	Secondary antibody coupled to Alexa Fluor 647

Results

7A Arl13b Smo^bnb ©

7A Merge Smo^bnb ©

Specimen 7A Smo^bnb: embryonic day 9.5; Smo^bnb/Smo^bnb (more

)
Note: Ventral spinal cord. Triple labeled: magenta - Arl13b; green - Smo (assay MGI:7734742); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	7A Arl13b Smo^bnb , 7A Merge Smo^bnb	Expression is seen in the cilia.

7A Arl13b Smo^cbb ©

7A Merge Smo^cbb ©

Specimen 7A Smo^cbb: embryonic day 9.5; Smo^cbb/Smo^cbb (more

)
Note: Ventral spinal cord. Triple labeled: magenta - Arl13b; green - Smo (assay MGI:7734742); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	7A Merge Smo^cbb , 7A Arl13b Smo^cbb	Expression is seen in the cilia.

7A Arl13b Smo^WT ©

7A Merge Smo^WT ©

7A Smo^WT ©

Specimen 7A Smo^WT: embryonic day 9.5 (more

)
Note: Ventral spinal cord. Triple labeled: magenta - Arl13b; green - Smo (assay MGI:7734742); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	7A Arl13b Smo^WT , 7A Smo^WT , 7A Merge Smo^WT	Expression is seen in the cilia.

7A Arl13b Ptch1^-/- ©

7A Merge Ptch1^-/- ©

Specimen 7A Ptch1^-/-: embryonic day 9.5; Ptch1^tm1Mps/Ptch1^tm1Mps (more

)
Note: Ventral spinal cord. Triple labeled: magenta - Arl13b; green - Smo (assay MGI:7734742); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	7A Merge Ptch1^-/- , 7A Arl13b Ptch1^-/-	Expression is seen in the cilia.

S9A Arl13b Smo^WT ©

S9A Merge Smo^WT ©

S9A Smo^WT ©

Specimen S9A Smo^WT: embryonic day 9.5 (more

)
Note: Dorsal spinal cord. Triple labeled: red - Arl13b; green - Smo (assay MGI:7734742); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	S9A Smo^WT , S9A Merge Smo^WT , S9A Arl13b Smo^WT	Expression is seen in the cilia.

S9A Arl13b Smo^bnb ©

S9A Merge Smo^bnb ©

Specimen S9A Smo^bnb: embryonic day 9.5; Smo^bnb/Smo^bnb (more

)
Note: Dorsal spinal cord. Triple labeled: red - Arl13b; green - Smo (assay MGI:7734742); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	S9A Arl13b Smo^bnb , S9A Merge Smo^bnb	Expression is seen in the cilia.

S9B Arl13b Smo^bnb ©

S9B Merge Smo^bnb ©

Specimen S9B Smo^bnb: embryonic day 9.5; Smo^bnb/Smo^bnb (more

)
Note: Triple labeled: yellow - Arl13b; magenta - Smo (assay MGI:7734748); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	S9B Arl13b Smo^bnb , S9B Merge Smo^bnb	Expression is seen in the cilia.

Specimen S9B Smo^cbb: embryonic day 9.5; Smo^cbb/Smo^cbb (more

)
Note: Triple labeled: yellow - Arl13b; magenta - Smo (assay MGI:7734748); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	S9B Arl13b Smo^cbb , S9B Merge Smo^cbb	Expression is seen in the cilia.

Specimen S9B Smo^WT: embryonic day 9.5 (more

)
Note: Triple labeled: yellow - Arl13b; magenta - Smo (assay MGI:7734748); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	S9B Arl13b Smo^WT , S9B Merge Smo^WT	Expression is seen in the cilia.

Specimen S9B Ptch1^-/-: embryonic day 9.5; Ptch1^tm1Mps/Ptch1^tm1Mps (more

)
Note: Triple labeled: yellow - Arl13b; magenta - Smo (assay MGI:7734748); blue - Hoechst.

Structure	Level	Pattern	Image	Note
TS15: neural tube	Present	Spotted	S9B Arl13b Ptch1^-/- , S9B Merge Ptch1^-/-	Expression is seen in the cilia.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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