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Gene Expression Data
Assay Details
Assay
Reference: J:350482 Chander A, et al., Loss of KANSL3 leads to defective inner cell mass and early embryonic lethality. Mol Reprod Dev. 2024 May;91(5):e23760
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7665322
Gene symbol: Cdx2
Gene name: caudal type homeobox 2
Antibody: anti-Cdx2 (CDX2-88)
Detection system: Alexa Fluor
Results
Specimen 3a CONTROL: embryonic day 3.5 (more )
Note: Double labeled: white - Cdx2; red - Sox2 (assay MGI:7665321).
Structure Level Pattern Image Note
TS4: trophectoderm Present 3a CONTROL CDX2 , 3a CONTROL MERGED
Specimen 3a MUT: embryonic day 3.5; Kansl3em1(IMPC)J/Kansl3em1(IMPC)J (more )
Note: Double labeled: white - Cdx2; red - Sox2 (assay MGI:7665321).
Structure Level Pattern Image Note
TS4: trophectoderm Present 3a MUT MERGED , 3a MUT CDX2 Expression level and number of expressing cells not significanty different from controls.
Specimen 4a CONTROL: embryonic day 3.5 (more )
Note: Triple labeled: white - Cdx2; red - Sox2 (assay MGI:7665321); green - Phospho-H3.
Structure Level Pattern Image Note
TS4: trophectoderm Present 4a CONTROL CDX2 , 4a CONTROL MERGED
Specimen 4a MUT: embryonic day 3.5; Kansl3em1(IMPC)J/Kansl3em1(IMPC)J (more )
Note: Triple labeled: white - Cdx2; red - Sox2 (assay MGI:7665321); green - Phospho-H3.
Structure Level Pattern Image Note
TS4: trophectoderm Present 4a MUT CDX2 , 4a MUT MERGED
Specimen 5a CONTROL: embryonic day 3.5 (more )
Note: Triple labeled: white - Cdx2; red - Sox2 (assay MGI:7665321); green - H4k5ac.
Structure Level Pattern Image Note
TS4: trophectoderm Present 5a CONTROL CDX2 , 5a CONTROL MERGED
Specimen 5a MUT: embryonic day 3.5; Kansl3em1(IMPC)J/Kansl3em1(IMPC)J (more )
Note: Triple labeled: white - Cdx2; red - Sox2 (assay MGI:7665321); green - H4k5ac.
Structure Level Pattern Image Note
TS4: trophectoderm Present 5a MUT MERGED , 5a MUT CDX2
Specimen 5c CONTROL: embryonic day 3.5 (more )
Note: Triple labeled: white - Cdx2; red - Sox2 (assay MGI:7665321); green - H4k8ac.
Structure Level Pattern Image Note
TS4: trophectoderm Present 5c CONTROL MERGED , 5c CONTROL CDX2
Specimen 5c MUT: embryonic day 3.5; Kansl3em1(IMPC)J/Kansl3em1(IMPC)J (more )
Note: Triple labeled: white - Cdx2; red - Sox2 (assay MGI:7665321); green - H4k8ac.
Structure Level Pattern Image Note
TS4: trophectoderm Present 5c MUT CDX2 , 5c MUT MERGED
Specimen 5e CONTROL: embryonic day 3.5 (more )
Note: Double labeled: white - Cdx2; green - H4k12ac.
Structure Level Pattern Image Note
TS4: trophectoderm Present 5e CONTROL CDX2 , 5e CONTROL MERGED
Specimen 5e MUT: embryonic day 3.5; Kansl3em1(IMPC)J/Kansl3em1(IMPC)J (more )
Note: Double labeled: white - Cdx2; green - H4k12ac.
Structure Level Pattern Image Note
TS4: trophectoderm Present 5e MUT MERGED , 5e MUT CDX2 p
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory