About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:171421 Vandunk C, et al., Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J Neurosci. 2011 Apr 27;31(17):6457-67
Assay type: RNA in situ
MGI Accession ID: MGI:7661038
Gene symbol: Fzd5
Gene name: frizzled class receptor 5
Probe: IMAGE clone 445088
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Two possible probes were referenced: MGI:270424 and MGI:7660796. The probe used in this assay was not specified.
Results
Specimen 6C E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon floor plate Present Regionally restricted 6C E10.5 Fzd5 Expression was detected in a region surrounding the base of the third ventricle.
Specimen 6C E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6C E11.5 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the dorsoventral dimension.
Specimen 6C E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon floor plate Present Regionally restricted 6C E12.5 Fzd5 At E12.5, expression was still present beneath the third ventricle but was restricted to the dorsal region overlapping with the Six3/Six6 region only.
Specimen 6C E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon floor plate Present Regionally restricted 6C E13.5 Fzd5 At E13.5, expression was still present beneath the third ventricle but was restricted to the dorsal region overlapping with the Six3/Six6 region only.
Specimen 6D E11.5 Rostral 1: embryonic day 11.5 (more )
Note: Rostral-most section of a rostral-caudal series beginning from rostral eye fields level.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 Rostral 1 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 2: embryonic day 11.5 (more )
Note: Second section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 2 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 3: embryonic day 11.5 (more )
Note: Third section of a rostral-caudal series.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 3 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 4: embryonic day 11.5 (more )
Note: Fourth section of a rostral-caudal series.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 4 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E11.5 Caudal 5: embryonic day 11.5 (more )
Note: Caudal-most section of a rostral-caudal series ending at developing pituitary.
Structure Level Pattern Image Note
TS19: diencephalon floor plate Present Regionally restricted 6D E11.5 Caudal 5 Fzd5 Expression continued to define the suprachiasmatic nucleus proliferative zone in the rostrocaudal dimension.
Specimen 6D E13.5 Rostral 1: embryonic day 13.5 (more )
Note: Rostral-most section of a rostral-caudal series beginning from rostral eye fields level.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 Rostral 1 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 2: embryonic day 13.5 (more )
Note: Second section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 2 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 3: embryonic day 13.5 (more )
Note: Third section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 3 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 4: embryonic day 13.5 (more )
Note: Fourth section of a rostral-caudal series. This section contained the suprachiasmatic nucleus progenitor region.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 4 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Specimen 6D E13.5 Caudal 5: embryonic day 13.5 (more )
Note: Caudal-most section of a rostral-caudal series ending at developing pituitary.
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 6D E13.5 Caudal 5 Fzd5 Expression was still present beneath the third ventricle but was restricted to the dorsal region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory