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Gene Expression Data
Assay Details
Assay
Reference: J:160964 Li J, et al., Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8916-21
Assay type: RNA in situ
MGI Accession ID: MGI:7628746
Gene symbol: Plxna2
Gene name: plexin A2
Probe: PlexinA2 cDNA
Probe preparation: Antisense RNA
Results
Specimen 4F: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: 3rd branchial arch mesenchyme derived from neural crest neural crest cell Present Regionally restricted 4F Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries.
TS19: 4th branchial arch mesenchyme derived from neural crest neural crest cell Present Regionally restricted 4F Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries.
TS19: 6th arch artery neural crest cell Present Regionally restricted 4F Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries.
TS19: branchial arch mesenchyme neural crest cell Present Regionally restricted 4F Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries.
Specimen 4H: embryonic day 11.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: 3rd branchial arch mesenchyme derived from neural crest neural crest cell Present Regionally restricted 4H Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries, similar as in the wild-type.
TS19: 4th branchial arch mesenchyme derived from neural crest neural crest cell Present Regionally restricted 4H Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries, similar as in the wild-type.
TS19: 6th arch artery neural crest cell Present Regionally restricted 4H Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries, similar as in the wild-type.
TS19: branchial arch mesenchyme neural crest cell Present Regionally restricted 4H Expressed in the pharyngeal mesenchyme surrounding the aortic arch arteries, similar as in the wild-type.
Specimen 4J: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: aortico-pulmonary spiral septum neural crest cell Present Regionally restricted 4J Expressed in the cells forming the nascent septum that divides the truncus arteriosus into the aorta and pulmonary artery.
Specimen 4L: embryonic day 11.5; MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: outflow tract neural crest cell Present Regionally restricted 4L Neural crest cells migrated appropriately to the cardiac outflow tract as two columns of positive cells, but the aorticopulmonary septum failed to develop.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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