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Gene Expression Data
Assay Details
Assay
Reference: J:333714 Huynh H, et al., DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 2023 Feb;175:44-48
Assay type: RT-PCR
MGI Accession ID: MGI:7620359
Gene symbol: Sesn2
Gene name: sestrin 2
Probe: Sesn2-pF, Sesn2-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to 18S RNA.
Results Image: 2E Sesn2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Ctrl P10 TS28: heart Present Not Specified; total RNA involves: C57BL/6NCrl Not Specified
cKO P10 TS28: heart Present Not Specified; total RNA involves: C57BL/6NCrl * MF1 Dele1em1Xfa/Dele1em1Xfa, Tg(myl7.L-cre)1118Tmhn/0Not Specified Conditional mutant.
TKO P10 TS28: heart Strong (a) Not Specified; total RNA involves: C57BL/6NCrl * MF1 Tafazzinem1Xfa/Tafazzinem1Xfa, Tg(myl7.L-cre)1118Tmhn/0Not Specified Conditional mutant.
dcKO P10 TS28: heart Present (b) Not Specified; total RNA involves: C57BL/6NCrl * MF1 Dele1em1Xfa/Dele1em1Xfa, Tafazzinem1Xfa/Tafazzinem1Xfa, Tg(myl7.L-cre)1118Tmhn/0Not Specified Conditional mutant.
Notes:
(a) Authors report activation of eIR2a-ATF signaling.
(b) Activation of eIR2a-ATF signaling was abolished.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory