Dele1^em1Xfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dele1^em1Xfa
• Name: DAP3 binding cell death enhancer 1; endonuclease-mediated mutation 1, Xi Fang
• MGI ID: MGI:7520211
• Synonyms: Dele1^f
• Gene: Dele1 Location: Chr18:38383302-38395682 bp, + strand Genetic Position: Chr18, 20.15 cM, cytoband B3
• Alliance: Dele1^em1Xfa page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 5 was flanked by loxP sites via CRISPR/Cas9 technology. (J:333714)

Expression

In Mice Carrying this Mutation:

51 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dele1 Mutation: 15 strains or lines available

References

• Original: J:333714 Huynh H, et al., DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 2023 Feb;175:44-48
• All: 1 reference(s)