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Gene Expression Data
Assay Details
Assay
Reference: J:331053 Chandrasekaran P, et al., CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth. Development. 2022 Nov 1;149(21):dev200909
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7616686
Gene symbol: Emcn
Gene name: endomucin
Antibody: anti-Emcn (AF4666)
Detection system: Secondary antibody
Results
Specimen S1A: embryonic day 12.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684); green - Vwf (assay MGI:7616685).
Structure Level Pattern Image Note
TS20: lung vascular element Present Regionally restricted S1A Expression in capillary and venous endothelium.

Specimen S1B: embryonic day 13.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684); green - Vwf (assay MGI:7616685).
Structure Level Pattern Image Note
TS21: lung vascular element Present Regionally restricted S1B Expression in capillary and venous endothelium.

Specimen S1C: embryonic day 15.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684); green - Erg (assay MGI:7616687).
Structure Level Pattern Image Note
TS23: lung vascular element Present S1C

Specimen S1D: embryonic day 15.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684); green - Erg (assay MGI:7616687).
Structure Level Pattern Image Note
TS23: lung vascular element Present S1D

Specimen S1E: embryonic day 17.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684); green - Erg (assay MGI:7616687).
Structure Level Pattern Image Note
TS25: lung vascular element Present S1E

Specimen S1F: embryonic day 17.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684); green - Erg (assay MGI:7616687).
Structure Level Pattern Image Note
TS25: lung vascular element Present S1F

Specimen S1G: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Double labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684).
Structure Level Pattern Image Note
TS26: lung vascular element Present S1G

Specimen S1H: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Double labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684).
Structure Level Pattern Image Note
TS26: lung vascular element Present S1H

Specimen S1I: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Double labeled: white - Emcn; red - Cxcl12 reporter (assay MGI:7616684).
Structure Level Pattern Image Note
TS26: lung vascular element Present S1I

Specimen S1J/K: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Triple labeled: white - Emcn; green - Acta2 (assay MGI:7616688); red - Cxcl12 reporter (assay MGI:7616684).
Structure Level Pattern Image Note
TS26: lung vascular element Present S1J , S1K

Specimen 5I (upper): embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Note: Double labeled: white - Emcn; green - Vwf (assay MGI:7616685).
Structure Level Pattern Image Note
TS26: lung vascular element Present 5I (upper)

Specimen 5I (lower): embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12tm2.1Sjm (more )
Note: Double labeled: white - Emcn; green - Vwf (assay MGI:7616685).
Structure Level Pattern Image Note
TS26: lung vascular element Present 5I (lower)

Specimen 6F: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12tm2.1Sjm (more )
Note: Triple labeled: white - Emcn; red - Erg (assay MGI:7616687); green - EdU.
Structure Level Pattern Image Note
TS26: lung vascular element Present 6F

Specimen 6G: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12tm2.1Sjm (more )
Note: Double labeled: white - Emcn; green - EdU.
Structure Level Pattern Image Note
TS26: lung vascular element Present 6G

Specimen 6H: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12tm2.1Sjm (more )
Note: Triple labeled: white - Emcn; red - Erg (assay MGI:7616687); green - EdU.
Structure Level Pattern Image Note
TS26: lung vascular element Present 6H

Specimen 6I: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12tm2.1Sjm (more )
Note: Double labeled: white - Emcn; green - EdU.
Structure Level Pattern Image Note
TS26: lung vascular element Present 6I

Specimen 7C: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12+, Tg(Tek-cre)12Flv/0 (more )
Structure Level Pattern Image Note
TS26: lung vascular element Present 7C

Specimen 7D: embryonic day 18.5; Cxcl12tm2.1Sjm/Cxcl12tm1.1Sjm, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lung vascular element Present 7D


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory