About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:302618 Wang B, et al., The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway. Autophagy. 2018;14(5):796-811
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7616440
Gene symbol: Chl1
Gene name: cell adhesion molecule L1-like
Antibody: Anti-Neural Cell Adhesion Molecule L1, clone 324 (MAB5272)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6E E18.5 Control: embryonic day 18.5 (more )
Note: Double labeled: red - Chl1; green - Gfap (assay MGI:7616441).
Structure Level Pattern Image Note
TS26: corpus callosum Present 6E E18.5 control
Specimen 6E E18.5 DKO: embryonic day 18.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Note: Double labeled: red - Chl1; green - Gfap (assay MGI:7616441).
Structure Level Pattern Image Note
TS26: corpus callosum Present 6E E18.5 DKO The corpus callosum was thinner compared to that in littermate controls.
Specimen 6E P0 Control: postnatal day 0 (more )
Note: Double labeled: red - Chl1; green - Gfap (assay MGI:7616441).
Structure Level Pattern Image Note
TS27: corpus callosum Present 6E P0 control
Specimen 6E P0 Ulk1/2-cDKO: postnatal day 0; Tg(Nes-cre)1Kln/0, Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1Thsn (more )
Note: Conditional mutant. Double labeled: red - Chl1; green - Gfap (assay MGI:7616441).
Structure Level Pattern Image Note
TS27: corpus callosum Present 6E P0 cDKO Dysgenesis was seen.
Specimen 6F E15.5 Control: embryonic day 15.5 (more )
Note: Double labeled: red - Chl1; green - Calr (assay MGI:7616442).
Structure Level Pattern Image Note
TS23: allocortex Present 6F E15.5 control
Specimen 6F E15.5 DKO: embryonic day 15.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Note: Double labeled: red - Chl1; green - Calr (assay MGI:7616442).
Structure Level Pattern Image Note
TS23: allocortex Present 6F E15.5 DKO
Specimen 6F E18.5 Control: embryonic day 18.5 (more )
Note: Double labeled: red - Chl1; green - Calr (assay MGI:7616442).
Structure Level Pattern Image Note
TS26: corpus callosum Present 6F E18.5 control
Specimen 6F E18.5 DKO: embryonic day 18.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Note: Double labeled: red - Chl1; green - Calr (assay MGI:7616442).
Structure Level Pattern Image Note
TS26: corpus callosum Present 6F E18.5 DKO The corpus callosum was thinner compared to that in littermate controls.
Specimen S1C Control: embryonic day 18.5 (more )
Note: Double labeled: red - Chl1; green - Nefm (assay MGI:7616450).
Structure Level Pattern Image Note
TS26: forebrain Present S1C control
Specimen S1C DKO: embryonic day 18.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Note: Double labeled: red - Chl1; green - Nefm (assay MGI:7616450).
Structure Level Pattern Image Note
TS26: forebrain Present Regionally restricted S1C DKO Mutant corticothalamic and thalamocortical axons were disorganized, overfasciculated, and traversed the pallial-subpallial boundary more anteroventrally than axons in littermate controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory