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Gene Expression Data
Assay Details
Assay
Reference: J:302618 Wang B, et al., The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway. Autophagy. 2018;14(5):796-811
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7616442
Gene symbol: Calr
Gene name: calreticulin
Antibody: Anti-Calretinin (AB5054)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6F E15.5 Control: embryonic day 15.5 (more )
Note: Double labeled: green - Calr; red - Chl1 (assay MGI:7616440).
Structure Cell Type Level Pattern Image Note
TS23: allocortex guidepost cell Present 6F E15.5 control
Specimen 6F E15.5 DKO: embryonic day 15.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Note: Double labeled: green - Calr; red - Chl1 (assay MGI:7616440).
Structure Cell Type Level Pattern Image Note
TS23: allocortex guidepost cell Present 6F E15.5 DKO Similar as in the control.
Specimen 6F E18.5 Control: embryonic day 18.5 (more )
Note: Double labeled: green - Calr; red - Chl1 (assay MGI:7616440).
Structure Cell Type Level Pattern Image Note
TS26: allocortex guidepost cell Present 6F E18.5 control
Specimen 6F E18.5 DKO: embryonic day 18.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Note: Double labeled: green - Calr; red - Chl1 (assay MGI:7616440).
Structure Cell Type Level Pattern Image Note
TS26: allocortex guidepost cell Present 6F E18.5 DKO Similar as in the control.
Specimen 7D Control: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 7D left Expressed in the thalamocortical axon.
Specimen 7D DKO: embryonic day 18.5; Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1.1Thsn (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 7D right Dramatic reduction in the number of positive thalamocortical axon projections reaching the cortex in the mutant after crossing the pallial-subpallial boundary than did in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory