Mip Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:276637 Matsuyama M, et al., Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. J Biol Chem. 2013 Dec 13;288(50):35626-35
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7608461
Gene symbol:	Mip
Gene name:	major intrinsic protein of lens fiber

Antibody:	Anti-AQP0/MIP
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

6A-1 ©

6A-3 ©

Specimen 6A WT/WT: postnatal month 4 (more

)
Note: Anterior region. Double labeled: green - Mip; red - Vim (assay MGI:7608460).

Structure	Level	Pattern	Image	Note
TS28: lens fiber	Present		6A-1 , 6A-3

6A-4 ©

6A-6 ©

Specimen 6A WT/SA: postnatal month 4; Vim^tm1Sibg/Vim⁺ (more

)
Note: Anterior region. Double labeled: green - Mip; red - Vim (assay MGI:7608460).

Structure	Level	Pattern	Image	Note
TS28: lens fiber	Present		6A-4 , 6A-6

6A-7 ©

6A-9 ©

Specimen 6A SA/SA: postnatal month 4; Vim^tm1Sibg/Vim^tm1Sibg (more

)
Note: Anterior region. Double labeled: green - Mip; red - Vim (assay MGI:7608460).

Structure	Level	Pattern	Image	Note
TS28: lens fiber	Present		6A-7 , 6A-9	Disorganization of lens fiber cells were seen in the homozygous mutant.

6B-1 ©

6B-3 ©

Specimen 6B WT/WT: postnatal month 4 (more

)
Note: Equatorial region. Double labeled: green - Mip; red - Vim (assay MGI:7608460).

Structure	Level	Pattern	Image	Note
TS28: lens fiber	Present		6B-3 , 6B-1

6B-4 ©

6B-6 ©

Specimen 6B WT/SA: postnatal month 4; Vim^tm1Sibg/Vim⁺ (more

)
Note: Equatorial region. Double labeled: green - Mip; red - Vim (assay MGI:7608460).

Structure	Level	Pattern	Image	Note
TS28: lens fiber	Present		6B-4 , 6B-6

6B-7 ©

6B-9 ©

Specimen 6B SA/SA: postnatal month 4; Vim^tm1Sibg/Vim^tm1Sibg (more

)
Note: Equatorial region. Double labeled: green - Mip; red - Vim (assay MGI:7608460).

Structure	Level	Pattern	Image	Note
TS28: lens fiber	Present		6B-7 , 6B-9	Disorganization of lens fiber cells were seen in the homozygous mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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