About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:308818 Moreau MX, et al., Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition. Development. 2021 Jul 15;148(14):dev197962
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7606763
Gene symbol: Nfib
Gene name: nuclear factor I/B
Results
Specimen 4A top: embryonic day 12.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wnt3atm1(cre)Eag/Wnt3a+ (more )
Note: Conditional mutant. Double labeled: green - Nfib; red - Rosa26tdTomato.
Structure Cell Type Level Pattern Image Note
TS20: telencephalon Cajal-Retzius cell Present Regionally restricted 4A top left , 4A top right Merge , 4A top right Nfib All tomato-positive (hem-derived Cajal-Retzius) cells also express Nfib.
Specimen 4A bottom: embryonic day 12.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Wnt3atm1(cre)Eag/Wnt3a+ (more )
Note: Conditional mutant. Double labeled: green - Nfib; red - Rosa26tdTomato.
Structure Cell Type Level Pattern Image Note
TS20: telencephalon Cajal-Retzius cell Present Regionally restricted 4A bottom right b Merge , 4A bottom right a Merge , 4A bottom right a Nfib , 4A bottom left , 4A bottom right b Nfib All tomato-positive (hem-derived Cajal-Retzius) cells also express Nfib.
Specimen 4B top: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp73tm1(cre)Agof/Trp73+ (more )
Note: Conditional mutant. Double labeled: red - Nfib; green - Rosa26YFP.
Structure Cell Type Level Pattern Image Note
TS20: telencephalon Cajal-Retzius cell Present Regionally restricted 4B top left , 4B top right Merge , 4B top right Nfib The deltaNp73Cre line, which labels Cajal-Retzius cells from the hem, septum and thalamic eminence, allowed the identification of some Nfib-negative Cajal-Retzius cells at all mediolateral levels.
Specimen 4B bottom: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Trp73tm1(cre)Agof/Trp73+ (more )
Note: Conditional mutant. Double labeled: red - Nfib; green - Rosa26YFP.
Structure Cell Type Level Pattern Image Note
TS20: telencephalon Cajal-Retzius cell Present Regionally restricted 4B bottom right b Nfib , 4B bottom right a Merge , 4B bottom left , 4B bottom right a Nfib , 4B bottom right b Merge The deltaNp73Cre line, which labels Cajal-Retzius cells from the hem, septum and thalamic eminence, allowed the identification of some Nfib-negative Cajal-Retzius cells at all mediolateral levels.
Specimen 4D top: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: red - Nfib; blue - Bhlhe22 (assay MGI:7606796); green - Rosa26YFP.
Structure Level Pattern Image Note
TS20: pallium Present Regionally restricted 4D top right Nfib , 4D top right Merge , 4D top left Emx1Cre recombines mostly in lateral and dorsal pallium progenitors; 96% of Nfib+ and 93% of Bhlhe22+ cells were from the Emx1 lineage.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory