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Gene Expression Data
Assay Details
Assay
Reference: J:233142 Hilton MJ, et al., Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med. 2008 Mar;14(3):306-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7593623
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen not shown WT: embryonic day 18.5; Notch1tm2Rko/Notch1tm2Rko, Notch2tm3Grid/Notch2tm3Grid (more )
Structure Level Pattern Image Note
TS26: tibia Ambiguous

Specimen not shown PNN: embryonic day 18.5; Notch1tm2Rko/Notch1tm1Con, Notch2tm3Grid/Notch2tm3Grid, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Ambiguous No difference in apoptosis of trabecular osteoblasts between mutant and wild-type mice.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory