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Gene Expression Data
Assay Details
Assay
Reference: J:129202 Dunty WC Jr, et al., Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development. 2008 Jan;135(1):85-94
Assay type: RNA in situ
MGI Accession ID: MGI:7574747
Gene symbol: Tbx18
Gene name: T-box18
Probe: Tbx18 probe
Probe preparation: Antisense RNA
Results
Specimen 3G: embryonic day 8.0 (more )
Note: 5-7 somites. Double labeled: purple - Tbx18; orange - Uncx (assay MGI:7574674).
Structure Level Pattern Image Note
TS12: somite Present Regionally restricted 3G Expressed in the anterior half of somites.
Specimen 3H: embryonic day 8.0; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: 5-7 somites. Double labeled: purple - Tbx18; orange - Uncx (assay MGI:7574674).
Structure Level Pattern Image Note
TS12: somite Present Regionally restricted 3H Expressed in the anterior half of somites. Segment polarity was well preserved in the anterior Wnt3a-/- somites.
Specimen 3I: embryonic day 8.0; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 5-7 somites. Double labeled: purple - Tbx18; orange - Uncx (assay MGI:7574674).
Structure Level Pattern Image Note
TS12: somite Present 3I Segment polarity was aberrant and less well defined in the anterior LOF somites. Interspersed, fuzzy stripes were still detected posteriorly.
Specimen 3J: embryonic day 8.0; Ctnnb1tm1Mmt/Ctnnb1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 5-7 somites. Double labeled: purple - Tbx18; orange - Uncx (assay MGI:7574674).
Structure Level Pattern Image Note
TS12: paraxial mesenchyme Trace 3J Somitic expression was almost completely repressed in the GOF mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory