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Gene Expression Data
Assay Details
Assay
Reference: J:95889 Wines-Samuelson M, et al., Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Dev Biol. 2005 Jan 15;277(2):332-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7572485
Gene symbol: Calb2
Gene name: calbindin 2
Results
Specimen not shown control E13.5: embryonic day 13.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present
Specimen not shown PS1 cKO E13.5: embryonic day 13.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present Expression in the conditional knockout was comparable to control.
Specimen not shown control E17.5: embryonic day 17.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present
Specimen not shown PS1 cKO E17.5: embryonic day 17.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present Expression in the conditional knockout was comparable to control.
Specimen not shown PS1+/- E13.5: embryonic day 13.5; Psen1tm1Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present
Specimen not shown PS1-/- E13.5: embryonic day 13.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present Expression in the PS1-/- was comparable to control.
Specimen not shown PS1+/- E17.5: embryonic day 17.5; Psen1tm1Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present
Specimen not shown PS1-/- E17.5: embryonic day 17.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present Fewer immunopositive cells were present in the PS1-/- mice compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory