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Gene Expression Data
Assay Details
Assay
Reference: J:226892 Hammond VE, et al., Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex. Cereb Cortex. 2014 Dec;24(12):3289-300
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7572408
Gene symbol: Akt1
Gene name: thymoma viral proto-oncogene 1
Antibody: anti-pAkt (Ser473)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the phosphorylated form of the protein.
Results
Specimen 8C/E: postnatal day 207 (more )
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present 8C , 8E
Specimen 8D/F: postnatal day 207; Ndfip1tm1Sest/Ndfip1tm1Sest, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present 8D , 8F Prominent perinuclear staining was observed in some deep-layer neurons.
Specimen 8G: postnatal day 314 (more )
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present 8G
TS28: cortical layer V pyramidal neuron Weak 8G Weakly stained in cytoplasm and apical dendrite.
Specimen 8H: postnatal day 314; Emx1tm1.1(cre)Ito/Emx1+, Ndfip1tm1Sest/Ndfip1tm1Sest (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present 8H
TS28: cortical layer V pyramidal neuron Strong 8H Strong cytoplasmic and apical dendrite staining was evident.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory