About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:226892 Hammond VE, et al., Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex. Cereb Cortex. 2014 Dec;24(12):3289-300
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7571611
Gene symbol: Rbfox3
Gene name: RNA binding protein, fox-1 homolog (C. elegans) 3
Antibody: anti-NeuN
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A/B: postnatal day 30; Ndfip1tm1Sest/Ndfip1tm1Sest (more )
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present 2A , 2B
TS28: cortical layer V pyramidal neuron Present 2B , 2A
Specimen 2C/D: postnatal day 30; Emx1tm1.1(cre)Ito/Emx1+, Ndfip1tm1Sest/Ndfip1tm1Sest (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present 2C , 2D No gross morphological abnormalities were observed.
TS28: cortical layer V pyramidal neuron Present 2D , 2C Irregularly arranged neuronal somata with lacunae and compacted nuclei were shown. The normal orientation of the pyramidal apex toward the pial surface was less defined.
Specimen not shown: postnatal day 30; Ndfip1tm1Sest/Ndfip1tm1Sest (more )
Note: Summarized in Table 1.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present
Specimen not shown: postnatal day 30; Ndfip1tm1Sest/Ndfip1tm1Sest, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Summarized in Table 1.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present Similar as in the control.
Specimen not shown: postnatal day 60; Ndfip1tm1Sest/Ndfip1tm1Sest (more )
Note: Summarized in Table 1.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present
Specimen not shown: postnatal day 60; Ndfip1tm1Sest/Ndfip1tm1Sest, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Summarized in Table 1.
Structure Cell Type Level Pattern Image Note
TS28: neocortex neuron Present Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory