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Gene Expression Data
Assay Details
Assay
Reference: J:95889 Wines-Samuelson M, et al., Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons. Dev Biol. 2005 Jan 15;277(2):332-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7571581
Gene symbol: Reln
Gene name: reelin
Antibody: anti-CR-50
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Assay notes: Two antibodies were described: MGI:5702931 and MGI:3526687; either could have been used in this assay.
Results
Specimen 5A: embryonic day 13.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present 5A
Specimen 5B: embryonic day 13.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present 5B Expression in the conditional knockout was comparable to control.
Specimen 5C: embryonic day 17.5; Psen1tm2Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present 5C
Specimen 5D: embryonic day 17.5; Psen1tm2Shn/Psen1tm2.1Shn, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present 5D Expression in the conditional knockout was comparable to control.
Specimen 5G: embryonic day 13.5; Psen1tm1Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present 5G
Specimen 5H: embryonic day 13.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon marginal layer Cajal-Retzius cell Present 5H Expression in the PS1-/- was comparable to control.
Specimen 5I: embryonic day 17.5; Psen1tm1Shn/Psen1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present 5I
Specimen 5J: embryonic day 17.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Cell Type Level Pattern Image Note
TS25: telencephalon marginal layer Cajal-Retzius cell Present 5J Fewer Reln-positive cells were present in the PS1-/- mice compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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