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Gene Expression Data
Assay Details
Assay
Reference: J:252112 Kim JJ, et al., Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Dev Dyn. 2018 Jan;247(1):156-169
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7567364
Gene symbol: Fabp7
Gene name: fatty acid binding protein 7, brain
Antibody: anti-BLBP
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4M: embryonic day 13.5; Sufutm1Hui/Sufu+ (more )
Note: Double labeled: green - Fabp7; red - Tubb3 (assay MGI:7565851).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 4M Expression was detected in radial precursors. The spatial domains of Fabp7 (BLBP) and Tubb3 immunopositive cells could not be completely separated. A substantial area was Fabp7-positive but Tubb3-negative.
TS21: cerebellum ventricular layer Present Regionally restricted 4M Expression was detected in radial precursors. The spatial domains of Fabp7 (BLBP) and Tubb3 immunopositive cells could not be completely separated. A substantial area was Fabp7-positive but Tubb3-negative.
Specimen 4N: embryonic day 13.5; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant. Double labeled: green - Fabp7; red - Tubb3 (assay MGI:7565851).
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 4N Expression was detected in radial precursors. The spatial domains of Fabp7 (BLBP) and Tubb3 immunopositive cells could not be completely separated. A substantial area was Fabp7-positive but Tubb3-negative. The area of the Fabp7 only immunopositive domain, relative to the total cerebellar area per section, was increased 1.8-fold in mutant cerebella at E13.5.
TS21: cerebellum ventricular layer Present Regionally restricted 4N Expression was detected in radial precursors. The spatial domains of Fabp7 (BLBP) and Tubb3 immunopositive cells could not be completely separated. A substantial area was Fabp7-positive but Tubb3-negative. The area of the Fabp7 only immunopositive domain, relative to the total cerebellar area per section, was increased 1.8-fold in mutant cerebella at E13.5.
Specimen 4O: embryonic day 13.5; Sufutm1Hui/Sufu+ (more )
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 4O Expression was detected in radial precursors.
TS21: cerebellum ventricular layer Present Regionally restricted 4O Expression was detected in radial precursors.
Specimen 4P: embryonic day 13.5; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 4P Expression was upregulated in radial precursors in the mutant compared with control.
TS21: cerebellum ventricular layer Present Regionally restricted 4P Expression was upregulated in radial precursors in the mutant compared with control.
Specimen 7K: embryonic day 13.5; Gli3tm1Urt/?, Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant. Double labeled: green - Fabp7; red - Tubb3 (assay MGI:7565851).
Structure Level Pattern Image Note
TS21: cerebellum Present 7K Expression domain in SuFu<-/loxP>;Blbp-Cre;Gli3<delta699> cerebella was comparable to control mice.
Specimen 7L: embryonic day 13.5; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant. Double labeled: green - Fabp7; red - Tubb3 (assay MGI:7565851).
Structure Level Pattern Image Note
TS21: cerebellum Present 7L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory