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Gene Expression Data
Assay Details
Assay
Reference: J:252112 Kim JJ, et al., Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Dev Dyn. 2018 Jan;247(1):156-169
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7565851
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti Beta III tubulin
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4M: embryonic day 13.5; Sufutm1Hui/Sufu+ (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (assay MGI:7567364).
Structure Cell Type Level Pattern Image Note
TS21: cerebellum cerebellar neuron Present Regionally restricted 4M Expression was detected in cerebellar neurons. Substantial overlap was observed with Fabp7 (BLBP). However, there was an area that was Fabp7-positive, but Tubb3-negative.
Specimen 4N: embryonic day 13.5; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Fabp7 (assay MGI:7567364).
Structure Cell Type Level Pattern Image Note
TS21: cerebellum cerebellar neuron Present Regionally restricted 4N The area of the Fabp7-positive;Tubb3-negative domain, relative to the total cerebellar area per section, was increased 1.8-fold in the mutant at E13.5.
Specimen 7K: embryonic day 13.5; Gli3tm1Urt/?, Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Fabp7 (assay MGI:7567364).
Structure Level Pattern Image Note
TS21: cerebellum Present 7K Expression domain in SuFu<-/loxP>;Blbp-Cre;Gli3<delta699> cerebella was comparable to control mice.
Specimen 7L: embryonic day 13.5; Sufutm1Hui/Sufutm1.1Hui, Tg(Fabp7-cre)1Htz/0 (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Fabp7 (assay MGI:7567364).
Structure Level Pattern Image Note
TS21: cerebellum Present 7L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory