Dlc1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:189950 Sabbir MG, et al., Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform. BMC Biol. 2010;8:17
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:7563953
Gene symbol:	Dlc1
Gene name:	deleted in liver cancer 1

Reporter:	lacZ
	Direct Detection

Results

9i wt/gt ©

Specimen 9i wt/gt: embryonic day 10.5; Dlc1^Gt(XE082)Byg/Dlc1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		9i wt/gt

9i gt/gt ©

Specimen 9i gt/gt: embryonic day 10.5; Dlc1^Gt(XE082)Byg/Dlc1^Gt(XE082)Byg (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Strong	Regionally restricted	9i gt/gt	Authors report strong expression in anterior part of notochord, somites, liver, heart, lung, forebrain, placenta and tail bud.

Specimen 9iii wt/gt: embryonic day 10.5; Dlc1^Gt(XE082)Byg/Dlc1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		9iii (right) wt/gt

Specimen 9iii gt/gt: embryonic day 10.5; Dlc1^Gt(XE082)Byg/Dlc1^Gt(XE082)Byg (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Strong	Regionally restricted	9iii (right) gt/gt	Authors report strong expression in anterior part of notochord, somites, liver, heart, lung, forebrain, placenta and tail bud.

10iii wt/gt ©

Specimen 10iii wt/gt: embryonic day 10.5; Dlc1^Gt(XE082)Byg/Dlc1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: heart atrium	Present		10iii wt/gt	Expression in trabeculated ventricular wall and thin smooth atria wall.
TS17: primitive ventricle	Present		10iii wt/gt	Expression in trabeculated ventricular wall and thin smooth atria wall.

10iii gt/gt ©

Specimen 10iii gt/gt: embryonic day 10.5; Dlc1^Gt(XE082)Byg/Dlc1^Gt(XE082)Byg (more

)

Structure	Level	Pattern	Image	Note
TS17: heart atrium	Present		10iii gt/gt	Atrial and ventricular walls were thin and underdeveloped compared to control.
TS17: primitive ventricle	Present		10iii gt/gt	Atrial and ventricular walls were thin and underdeveloped compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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