Foxl2 Immunohistochemistry Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:284860 Okashita N, et al., TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression. Sci Rep. 2019 Sep 17;9(1):13462
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7563889
Gene symbol:	Foxl2
Gene name:	forkhead box L2

Antibody:	Anti-FOXL2 antibody (ab5096)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

4b XY ©

Specimen 4b Tet2^delta/+: embryonic day 13.5; Tet2^em1Mtac/Tet2⁺ (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: testis	Absent		4b XY

4b XY middle ©

Specimen 4b Tet2^delta/delta XY: embryonic day 13.5; Tet2^em1Mtac/Tet2^em1Mtac (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: testis	Absent		4b XY middle

4b XX ©

Specimen 4b Tet2^delta/delta XX: embryonic day 13.5; Tet2^em1Mtac/Tet2^em1Mtac (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: mesenchymal stroma of ovary	Present		4b XX

4d XY Jmjd1a^delta/+;Tet2^delta/delta ©

Specimen 4d Jmjd1a^delta/+;Tet2^delta/delta XY: embryonic day 13.5; Kdm3a^tm1.1Jsak/Kdm3a⁺, Tet2^em1Mtac/Tet2^em1Mtac (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: testis	Absent		4d XY Jmjd1a^delta/+;Tet2^delta/delta

4d XY Jmjd1a^delta/delta;Tet2^+/+ ©

Specimen 4d Jmjd1a^delta/delta;Tet2^+/+: embryonic day 13.5; Kdm3a^tm1.1Jsak/Kdm3a^tm1.1Jsak (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: testis	Present		4d XY Jmjd1a^delta/delta;Tet2^+/+	This mutant has a ovotestes composed of testicular cells and ovarian cells. The ratio of FOXL2-positive cells to SOX9-positive cells was increased in Tet2/Kdm3a-double deficient gonads as compared to Kdm3a-deficient gonads.

4d XY Jmjd1a^delta/delta;Tet2^delta/delta ©

Specimen 4d Jmjd1a^delta/delta;Tet2^delta/delta: embryonic day 13.5; Kdm3a^tm1.1Jsak/Kdm3a^tm1.1Jsak, Tet2^em1Mtac/Tet2^em1Mtac (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: testis	Present		4d XY Jmjd1a^delta/delta;Tet2^delta/delta	This mutant has a ovotestes composed of testicular cells and ovarian cells. The ratio of FOXL2-positive cells to SOX9-positive cells was increased in Tet2/Kdm3a-double deficient gonads as compared to Kdm3a-deficient gonads.

4d XX Jmjd1a^delta/+;Tet2^delta/delta ©

Specimen 4d Jmjd1a^delta/+;Tet2^delta/delta XX: embryonic day 13.5; Kdm3a^tm1.1Jsak/Kdm3a⁺, Tet2^em1Mtac/Tet2^em1Mtac (more

)
Note: Double labeled: magenta - Foxl2; green - Sox9 (assay MGI:7563886).

Structure	Level	Pattern	Image	Note
TS21: ovary	Present		4d XX Jmjd1a^delta/+;Tet2^delta/delta

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