Tet2^em1Mtac
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tet2^em1Mtac
• Name: tet methylcytosine dioxygenase 2; endonuclease-mediated mutation 1, Makoto Tachibana
• MGI ID: MGI:6400248
• Synonyms: Tet2delta
• Gene: Tet2 Location: Chr3:133169438-133250882 bp, - strand Genetic Position: Chr3, 61.84 cM
• Alliance: Tet2^em1Mtac page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a deletion of exon 3. (J:284860)

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tet2 Mutation: 778 strains or lines available

References

• Original: J:284860 Okashita N, et al., TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression. Sci Rep. 2019 Sep 17;9(1):13462
• All: 1 reference(s)