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Gene Expression Data
Assay Details
Assay
Reference: J:330412 Yang M, et al., Mice lacking DCAF2 in placenta die at the gastrulation stage. Cell Tissue Res. 2022 Sep;389(3):559-572
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7562595
Gene symbol: Dtl
Gene name: denticleless E3 ubiquitin protein ligase
Antibody: anti-DCAF2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2i': embryonic day 5.75; Dtltm1c(EUCOMM)Wtsi/Dtltm1c(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS8: ectoplacental cone Present 2i'
TS8: epiblast Present 2i'
TS8: extraembryonic ectoderm Present 2i'
Specimen 2i": embryonic day 5.75; Dtltm1c(EUCOMM)Wtsi/Dtltm1c(EUCOMM)Wtsi, Elf5em1(cre)Jilu/Elf5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS8: ectoplacental cone Trace 2i" Expression was hardly detected, almost equal to that in negative control.
TS8: epiblast Trace 2i" Expression was hardly detected, almost equal to that in negative control.
TS8: extraembryonic ectoderm Trace 2i" Expression was hardly detected, almost equal to that in negative control.
Specimen 3b: embryonic day 5.25 (more )
Structure Level Pattern Image Note
TS7: ectoplacental cone Weak 3b Only a small amount of expression was seen.
TS7: epiblast Weak 3b Only a small amount of expression was seen.
TS7: extraembryonic ectoderm Weak 3b Only a small amount of expression was seen.
Specimen 3d: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS7: ectoplacental cone Strong Ubiquitous 3d
TS7: epiblast Strong Ubiquitous 3d
TS7: extraembryonic ectoderm Strong Ubiquitous 3d
Specimen 3f: embryonic day 5.75 (more )
Structure Level Pattern Image Note
TS8: ectoplacental cone Strong 3f
TS8: embryo Strong 3f
TS8: epiblast Strong 3f
Specimen 3h: embryonic day 6.75 (more )
Structure Level Pattern Image Note
TS10: ectoplacental cone Strong 3h
TS10: embryo ectoderm Strong 3h
TS10: extraembryonic ectoderm Strong 3h
TS10: primitive streak Strong 3h
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory