Hoxd11 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:336421 Rodriguez-Carballo E, et al., Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes. BMC Biol. 2019 Jul 12;17(1):55
Assay type:	RNA in situ
MGI Accession ID:	MGI:7545584
Gene symbol:	Hoxd11
Gene name:	homeobox D11

Probe:	Hoxd11 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

S2A Hoxd11 ©

Specimen S2A Hoxd11 Wt: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Present		S2A Hoxd11

6B Hoxd11 Wt ©

Specimen 6B Hoxd11 Wt: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: forelimb	Present		6B Hoxd11 Wt

Specimen 6B Hoxd11 inv: embryonic day 12.5; In(2Itga6-Igs15)3Ddu/In(2Itga6-Igs15)3Ddu (more

)

Structure	Level	Pattern	Image	Note
TS20: forelimb	Present	Regionally restricted	6B Hoxd11 inv	Expression lost in proximal cells.
TS20: forelimb digit	Weak	Regionally restricted	6B Hoxd11 inv	Expression also reduced in distal cells (digits 2 and 5).

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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