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Gene Expression Data
Assay Details
Assay
Reference: J:293794 Durbin MD, et al., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531370
Gene symbol: Tnnt2
Gene name: troponin T2, cardiac
Antibody: anti-cTnt
Detection system: Secondary antibody
Results
Specimen 3C: embryonic day 12.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Cell Type Level Pattern Image Note
TS20: left ventricle cardiac muscle cardiac muscle cell Present 3C
Specimen 3D: embryonic day 12.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Cell Type Level Pattern Image Note
TS20: interventricular septum cardiac muscle cardiac muscle cell Present 3D
Specimen 3F: embryonic day 11.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Note: Double labeled: green - Tnnt2; red - Shroom3 reporter (assay MGI:7531371).
Structure Cell Type Level Pattern Image Note
TS19: left ventricle cardiac muscle cardiac muscle cell Present 3F , 3G
Specimen 7C: embryonic day 14.5 (more )
Note: Double labeled: green - Tnnt2; red - pHH3.
Structure Cell Type Level Pattern Image Note
TS22: left ventricle cardiac muscle cardiac muscle cell Present 7C
Specimen 7D: embryonic day 14.5; Shroom3Gt(ROSA53)Sor/Shroom3Gt(ROSA53)Sor (more )
Note: Double labeled: green - Tnnt2; red - pHH3.
Structure Cell Type Level Pattern Image Note
TS22: left ventricle cardiac muscle cardiac muscle cell Present 7D Increased rates of proliferation are seen in the mutant mice.
Specimen S2A: embryonic day 14.5 (more )
Note: Double labeled: green - Tnnt2; red - Casp3 (assay MGI:7531404).
Structure Cell Type Level Pattern Image Note
TS22: left ventricle cardiac muscle cardiac muscle cell Present S2F , S2A
Specimen S2B: embryonic day 14.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Note: Double labeled: green - Tnnt2; red - Casp3 (assay MGI:7531404).
Structure Cell Type Level Pattern Image Note
TS22: left ventricle cardiac muscle cardiac muscle cell Present S2G , S2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory