Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:293794 Durbin MD, et al., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7531404
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved Caspase-3 (Asp175; #9661)
Detection system:	Secondary antibody

Results

S2D ©

S2F ©

Specimen S2D: embryonic day 14.5 (more

)
Note: Double labeled: red - Casp3; green - Tnnt2 (assay MGI:7531370).

Structure	Cell Type	Level	Pattern	Image	Note
TS22: left ventricle cardiac muscle	cardiac muscle cell	Present	Single cells	S2F , S2D

S2E ©

S2G ©

Specimen S2E: embryonic day 14.5; Shroom3^{Gt(ROSA53)Sor}/Shroom3^{Gt(ROSA53)Sor} (more

)
Note: Double labeled: red - Casp3; green - Tnnt2 (assay MGI:7531370).

Structure	Cell Type	Level	Pattern	Image	Note
TS22: left ventricle cardiac muscle	cardiac muscle cell	Present	Single cells	S2E , S2G	There is trend, though not statistically significant, towards decreased apoptosis in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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