About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:276652 Fang Q, et al., Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506982
Gene symbol: Ctbp2
Gene name: C-terminal binding protein 2
Antibody: CtBP2 antibody Clone 16 (612044)
Assay notes: Fixation with 4% polyoxymethylene.
Results
Specimen 5a CtBP2 P14 WT: postnatal day 14 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P14 WT CtBP2 inset , 5a P14 WT Merged , 5a P14 WT CtBP2 , 5a P14 WT Merged inset Expression in pre-synaptic ribbons. Expression in lateral aspect of IHCs.
Specimen 5a CtBP2 P14 DKO: postnatal day 14; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P14 DKO CtBP2 inset , 5a P14 DKO CtBP2 , 5a P14 DKO Merged inset , 5a P14 DKO Merged No difference in expression compared to wild type from apical to basal turns.
Specimen 5a CtBP2 P30 WT: postnatal day 30 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P30 WT CtBP2 inset , 5a P30 WT Merged , 5a P30 WT Merged inset , 5a P30 WT CtBP2 Expression in pre-synaptic ribbons. Expression in lateral aspect of IHCs.
Specimen 5a CtBP2 P30 DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present Punctate 5a P30 DKO Merged , 5a P30 DKO Merged inset , 5a P30 DKO CtBP2 inset , 5a P30 DKO CtBP2 No difference in expression compared to wild type from apical to basal turns.
Specimen S4 CtBP2 APEX P14 WT: postnatal day 14 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P14 WT CtBP2 , S4_APEX P14 WT CtBP2 inset , S4_APEX P14 WT Merged , S4_APEX P14 WT Merged Inset
Specimen S4 CtBP2 APEX P14 DKO: postnatal day 14; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P14 DKO CtBP2 inset , S4_APEX P14 DKO CtBP2 , S4_APEX P14 DKO Merged inset , S4_APEX P14 DKO Merged
Specimen S4 CtBP2 APEX P30 WT: postnatal day 30 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P30 WT Merged inset , S4_APEX P30 WT CtBP2 inset , S4_APEX P30 WT CtBP2 , S4_APEX P30 WT Merged
Specimen S4 CtBP2 APEX P30 DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_APEX P30 DKO CtBP2 inset , S4_APEX P30 DKO CtBP2 , S4_APEX P30 DKO Merged inset , S4_APEX P30 DKO Merged
Specimen S4 CtBP2 MID P14 WT: postnatal day 14 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P14 WT Merged inset , S4_MID P14 WT CtBP2 inset , S4_MID P14 WT CtBP2 , S4_MID P14 WT Merged
Specimen S4 CtBP2 MID P14 DKO: postnatal day 14; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P14 DKO CtBP2 inset , S4_MID P14 DKO CtBP2 , S4_MID P14 DKO Merged inset , S4_MID P14 DKO Merged
Specimen S4 CtBP2 MID P30 WT: postnatal day 30 (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P30 WT CtBP2 inset , S4_MID P30 WT Merged , S4_MID P30 WT CtBP2 , S4_MID P30 WT Merged inset
Specimen S4 CtBP2 MID P30 DKO: postnatal day 30; Limk1tm1Zpj/Limk1tm1Zpj, Limk2tm1.1Tnak/Limk2tm1.1Tnak (more )
Note: Double labeled: red - Ctbp2; green - Dlg4 (PSD95 assay MGI:7506983).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S4_MID P30 DKO Merged inset , S4_MID P30 DKO Merged , S4_MID P30 DKO CtBP2 , S4_MID P30 DKO CtBP2 inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory