Tfap2d Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:177585 Hesse K, et al., AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7492151
Gene symbol:	Tfap2d
Gene name:	transcription factor AP-2, delta

Antibody:	anti-AP-2d
Detection system:	Secondary antibody

Results

S1d ©

Specimen S1d: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: midbrain	Present	Regionally restricted	S1d	Nuclear expression in midbrain.
TS20: thalamus	Present	Regionally restricted	S1d	Nuclear expression in dorsal thalamus.

2c ©

Specimen 2c: postnatal week 3 (more

)

Structure	Level	Image	Note
TS28: inferior colliculus	Present	2c	Expression restricted to inferior colliculus.
TS28: dorsal thalamus	Weak	2c	Lesser expression in superior colliculus and dorsal thalamus.
TS28: superior colliculus	Weak	2c	Lesser expression in superior colliculus and dorsal thalamus.

2d ©

Specimen 2d: postnatal week 3; Tfap2d^tm1Mos/Tfap2d^tm1Mos (more

)

Structure	Level	Pattern	Image	Note
TS28: brain	Absent		2d

3a E13 AP-2d ©

Specimen 3a AP-2d E13: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: midbrain	Present		3a E13 AP-2d

3a E15 AP-2d ©

Specimen 3a AP-2d E15: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: midbrain	Present	Regionally restricted	3a E15 AP-2d

3a E17 AP-2d ©

Specimen 3a AP-2d E17: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: midbrain	Present	Regionally restricted	3a E17 AP-2d

Specimen 3b AP-2d (left): embryonic day 17.5 (more

)
Note: Double labeled: red - Tfap2d; green - Tfap2a (assay MGI:7492152).

Structure	Level	Pattern	Image	Note
TS25: superior colliculus	Present		3b AP-2d (left) , 3b merge (left) , 3b merge (left) inset , 3b AP-2d (left) inset	Expression in anterior dorsal midbrain (superior colliculus).
TS25: inferior colliculus	Present		3b AP-2d (left) inset , 3b AP-2d (left) , 3b merge (left) inset , 3b merge (left)	Expresion in posterior midbrain (inferior colliculus).

Specimen 3b AP-2d (right): embryonic day 17.5 (more

)
Note: Double labeled: red - Tfap2d; green - Tfap2b (assay MGI:7492154).

Structure	Level	Pattern	Image	Note
TS25: superior colliculus	Present		3b AP-2d (right) inset , 3b AP-2d (right) , 3b merge (right) , 3b merge (right) inset	Expression in anterior dorsal midbrain (superior colliculus).
TS25: inferior colliculus	Present		3b AP-2d (right) inset , 3b AP-2d (right) , 3b merge (right) , 3b merge (right) inset	Expresion in posterior midbrain (inferior colliculus).

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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