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Gene Expression Data
Assay Details
Assay
Reference: J:177585 Hesse K, et al., AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7492152
Gene symbol: Tfap2a
Gene name: transcription factor AP-2, alpha
Antibody: anti-AP-2a
Detection system: Secondary antibody
Results
Specimen 2e: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: cerebellum Strong 2e Strong expression in anterior dorsal midbrain (superior colliculus) and cerebellum.
TS28: superior colliculus Strong 2e Strong expression in anterior dorsal midbrain (superior colliculus) and cerebellum.
TS28: inferior colliculus Absent 2e No expression in posterior midbrain (inferior colliculus).
Specimen 2f: postnatal week 3; Tfap2dtm1Mos/Tfap2dtm1Mos (more )
Structure Level Pattern Image Note
TS28: midbrain Present Widespread 2f Expression extends throughout entire mesencephalon.
Specimen 3b AP-2a: embryonic day 17.5 (more )
Note: Double labeled: green - Tfap2a; red - Tfap2d (assay MGI:7492151).
Structure Level Pattern Image Note
TS25: superior colliculus Present 3b merge (left) inset , 3b merge (left) , 3b AP-2a inset , 3b AP-2a Expression in anterior dorsal midbrain (superior colliculus).
TS25: inferior colliculus Absent 3b merge (left) , 3b AP-2a inset , 3b AP-2a , 3b merge (left) inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory