Tfap2dtm1Mos
Targeted Allele Detail
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Symbol: |
Tfap2dtm1Mos |
Name: |
transcription factor AP-2, delta; targeted mutation 1, Markus Moser |
MGI ID: |
MGI:5296818 |
Gene: |
Tfap2d Location: Chr1:19173246-19236570 bp, + strand Genetic Position: Chr1, 6.08 cM
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Alliance: |
Tfap2dtm1Mos page
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Tfap2dtm1Mos/Tfap2dtm1Mos mice lack the colliculus inferior
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:177585
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
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Mutation details: Exon 1 was disrupted by the insertion of an IRES-lacZ-neo cassette. The absence of transcript expression was confirmed by RT-PCR on E17 posterior midbrain extracts. X-gal staining confirmed the expression of lacZ in the entire midbrain of newborns.
(J:177585)
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Generation of Tfap2d deficient mice |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tfap2d Mutation: |
20 strains or lines available
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Original: |
J:177585 Hesse K, et al., AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483 |
All: |
2 reference(s) |
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