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Gene Expression Data
Assay Details
Assay
Reference: J:333946 Hattori Y, et al., CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7488358
Gene symbol: Mrc1
Gene name: mannose receptor, C type 1
Antibody: anti-CD206 (AF2535)
Detection system: Secondary antibody
Results
Specimen 1A E12.5 CD206: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: red - Mrc1; green - P2ry12 (assay MGI:7488357).
Structure Cell Type Level Pattern Image Note
TS20: pallium central nervous system macrophage Present Regionally restricted 1A E12.5 CD206 (upper) , 1A E12.5 CD206 (lower) , 1A E12.5 P2RY12/CD206 Expression in cells intermingled with P2ry12-expressing cells. Cells co-expressing P2ry12 frequently detected at E12.5 and E13.5.
Specimen 1A E13.5 CD206: embryonic day 13.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: red - Mrc1; green - P2ry12 (assay MGI:7488357).
Structure Cell Type Level Pattern Image Note
TS21: pallium central nervous system macrophage Present Regionally restricted 1A E13.5 CD206 , 1A E13.5 P2RY12/CD206 Expression in cells intermingled with P2ry12-expressing cells. Cells co-expressing P2ry12 frequently detected at E12.5 and E13.5.
Specimen 1A E14.5 CD206: embryonic day 14.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: red - Mrc1; green - P2ry12 (assay MGI:7488357).
Structure Cell Type Level Pattern Image Note
TS22: pallium central nervous system macrophage Present Regionally restricted 1A E14.5 P2RY12/CD206 Expression in cells intermingled with P2ry12-expressing cells.
Specimen S1A E14.5 CD206: embryonic day 14.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: red - Mrc1; green - P2ry12 (assay MGI:7488357).
Structure Cell Type Level Pattern Image Note
TS22: pallium central nervous system macrophage Present Regionally restricted S1A Expression in cells intermingled with P2ry12-expressing cells.
Specimen S1B E15.5 CD206: embryonic day 15.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: red - Mrc1; green - P2ry12 (assay MGI:7488357).
Structure Cell Type Level Pattern Image Note
TS23: pallium central nervous system macrophage Present Regionally restricted S1B E15.5 P2RY12/CD206 Expression in cells intermingled with P2ry12-expressing cells.
Specimen S1B E16.5 P2RY12: embryonic day 16.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: red - Mrc1; green - P2ry12 (assay MGI:7488357).
Structure Cell Type Level Pattern Image Note
TS24: pallium central nervous system macrophage Present Regionally restricted S1B E16.5 P2RY12/CD206 Expression in cells intermingled with P2ry12-expressing cells.
Specimen 1F E12.5 CD206: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: green - Mrc1; magenta - Lyve1 (assay MGI:7488359).
Structure Cell Type Level Pattern Image Note
TS20: brain meninges meningeal macrophage Present Regionally restricted 1F E12.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS20: lateral ventricle central nervous system macrophage Present Regionally restricted 1F E12.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS20: pallium central nervous system macrophage Present Regionally restricted 1F E12.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.
Specimen 1F E13.5 CD206: embryonic day 13.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: green - Mrc1; magenta - Lyve1 (assay MGI:7488359).
Structure Cell Type Level Pattern Image Note
TS21: telencephalon meninges meningeal macrophage Present Regionally restricted 1F E13.5 CD206/LYVE1 present / RR Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS21: lateral ventricle central nervous system macrophage Present Regionally restricted 1F E13.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS21: pallium central nervous system macrophage Present Regionally restricted 1F E13.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.
Specimen S1C E14.5 CD206: embryonic day 14.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: green - Mrc1; magenta - Lyve1 (assay MGI:7488359).
Structure Cell Type Level Pattern Image Note
TS22: telencephalon meninges meningeal macrophage Present Regionally restricted S1C E14.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS22: lateral ventricle central nervous system macrophage Present Regionally restricted S1C E14.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS22: pallium central nervous system macrophage Present Regionally restricted S1C E14.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.
Specimen S1C E15.5 CD206: embryonic day 15.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: green - Mrc1; magenta - Lyve1 (assay MGI:7488359).
Structure Cell Type Level Pattern Image Note
TS23: telencephalon meninges meningeal macrophage Present Regionally restricted S1C E15.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS23: lateral ventricle central nervous system macrophage Present Regionally restricted S1C E15.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS23: pallium central nervous system macrophage Present Regionally restricted S1C E15.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.
Specimen S1C E16.5 CD206: embryonic day 16.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Double labeled: green - Mrc1; magenta - Lyve1 (assay MGI:7488359).
Structure Cell Type Level Pattern Image Note
TS24: telencephalon meninges meningeal macrophage Present Regionally restricted S1C E16.5 CD206/LYVE1 Most Mrc1-expresssing cells in meninges simutaneously express Lyve1.
TS24: lateral ventricle central nervous system macrophage Present Regionally restricted S1C E16.5 CD206/LYVE1 About 3/4 of intraventricular Mrc1-expressing cells also express Lyve1.
TS24: pallium central nervous system macrophage Present Regionally restricted S1C E16.5 CD206/LYVE1 About 1/4 of parenchymal Mrc1-expressing cells co-express Lyve1.
Specimen 1M (left) CD206: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Triple labeled: red - Mrc1; green - Cx3cr1 reporter (assay MGI:7488349); cyan - Tjp1 (assay MGI:7488361).
Structure Cell Type Level Pattern Image Note
TS20: pallium central nervous system macrophage Present Regionally restricted 1M (left) Expression in cells attached to apical surface.
Specimen 1M (right) CD206: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+ (more )
Note: Triple labeled: red - Mrc1; green - Cx3cr1 reporter (assay MGI:7488349); cyan - Tjp1 (assay MGI:7488361).
Structure Cell Type Level Pattern Image Note
TS20: pallium central nervous system macrophage Present Regionally restricted 1M (right) Expression in intraventricular macrophages with extension of their thin protrusions reaching the subapical parenchyma.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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