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Gene Expression Data
Assay Details
Assay
Reference: J:213958 Lang RA, et al., p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. Development. 2014 Aug;141(16):3177-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486721
Gene symbol: Ctnnd1
Gene name: catenin delta 1
Antibody: Anti-p120 Catenin (610133)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5C: embryonic day 10.5; Ctnnd1tm1Abre/Ctnnd1tm1Abre (more )
Structure Level Pattern Image Note
TS17: lens pit Present 5C Localized mostly to the zonula adherens and did not appear to strongly colocalize with Shroom3 in prominent actomyosin filaments that spanned the apical cortex.
Specimen 5D: embryonic day 10.5; Ctnnd1tm1Abre/Ctnnd1tm1Abre, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Absent 5D
Specimen 5E: embryonic day 10.5; Ctnnd1tm1Abre/Ctnnd1+, Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Present 5E Average peak intensity revealed a 27.4% decrease in lens cell junctions compared with control cells.
Specimen S2E/E': embryonic day 10.5; Ctnnd1tm1Abre/Ctnnd1+ (more )
Structure Level Pattern Image Note
TS17: eye mesenchyme Present S2E' , S2E
TS17: lens pit Present S2E' , S2E
Specimen S2F/F': embryonic day 10.5; Ctnnd1tm1Abre/Ctnnd1tm1Abre, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: eye mesenchyme Absent S2F' , S2F
TS17: lens pit Present S2F' , S2F
Specimen S3B: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnd1; red - Myh10 (assay MGI:7486716).
Structure Level Pattern Image Note
TS16: lens placode Present S3B merge , S3B right
Specimen S3D: embryonic day 10.0 (more )
Note: Double labeled: green - Ctnnd1; red - Shroom3 (assay MGI:7486722).
Structure Level Pattern Image Note
TS16: lens placode Present S3D merge , S3D right
Specimen S3E/F: embryonic day 10.5 (more )
Note: Double labeled: green - Ctnnd1; red - Shroom3 (assay MGI:7486722).
Structure Level Pattern Image Note
TS17: lens pit Present S3F merge , S3E merge , S3F right , S3E right Localized mostly to the zonula adherens and did not appear to strongly colocalize with Shroom3 in prominent actomyosin filaments that spanned the apical cortex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory