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Gene Expression Data
Assay Details
Assay
Reference: J:146199 Barrionuevo F, et al., Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol. 2009 Mar 15;327(2):301-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464309
Gene symbol: Amh
Gene name: anti-Mullerian hormone
Antibody: anti-AMH/MIS (C-20; sc-6886)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Fixation with 3.7% formaldehyde.
Results
Specimen 4Ca: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: primary sex cord Present 4Ca
Specimen 4Cb: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: seminiferous cord Present 4Cb
Specimen 4Cc: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: seminiferous cord Present 4Cc
Specimen Sox9delta/delta not shown: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: seminiferous cord Present Down-regulation in expression not obvious.
Specimen Sox8-/- not shown: embryonic day 15.5; Sox8tm1Weg/Sox8tm1Weg (more )
Structure Level Pattern Image Note
TS23: seminiferous cord Present Down-regulation in expression not obvious.
Specimen 4Cd: embryonic day 13.0; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: primary sex cord Present 4Cd Authors report normal expression in testis cords at E13.0
Specimen 4Ce: embryonic day 14.0; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: seminiferous cord Weak 4Ce Significantly reduced expression compared to control.
Specimen 4Cf: embryonic day 15.5; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: seminiferous cord Weak 4Cf Significantly reduced expression compared to control.
Specimen 7Aa: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: testis Present 7Aa
Specimen 7Ab: postnatal day 6; Plekha5Tg(AMH-cre)1Flor/0, Sox8tm1Weg/Sox8+, Sox9tm1Gsr/Sox9tm1Gsr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: testis Present 7Ab Expression similar to that of control.
Specimen 7Ac: postnatal day 6; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: testis Weak 7Ac Weak expression compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory