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Gene Expression Data
Assay Details
Assay
Reference: J:146199 Barrionuevo F, et al., Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol. 2009 Mar 15;327(2):301-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464307
Gene symbol: Cyp11a1
Gene name: cytochrome P450, family 11, subfamily a, polypeptide 1
Antibody: anti-P450SCC (AB1244)
Detection system: Secondary antibody
Assay notes: Fixation with 3.7% formaldehyde.
Results
Specimen 2Cg: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 2Cg Authors report normal tubule architecture.
Specimen 2Ch: postnatal month 2; Plekha5Tg(AMH-cre)1Flor/0, Sox8tm1Weg/Sox8+, Sox9tm1Gsr/Sox9tm1Gsr (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: seminiferous tubule Present 2Ch Tubules lack development.
TS28: Leydig cell Leydig cell Present 2Ch High proportion of Leydig cells.
Specimen 2Ci: postnatal month 2; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: seminiferous tubule Present 2Ci Tubules lack development.
TS28: Leydig cell Leydig cell Present 2Ci High proportion of Leydig cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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