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Gene Expression Data
Assay Details
Assay
Reference: J:314694 Douchi D, et al., Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus. Gastroenterology. 2021 Dec;161(6):1907-1923.e26
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7461896
Gene symbol: Pgc
Gene name: progastricsin (pepsinogen C)
Reporter: mCherry
Probe: mCherry probe (431201)
Probe preparation: Antisense
Visualized with: Chromogenic
Results
Specimen S2C: postnatal adult; Pgctm1.1(cre/ERT2)Itoy/Pgc+ (more )
Note: Double labeled: red - Pgc; blue - Mki67 (assay MGI:7463941).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S2C Base , S2C Isthmus , S2C Expression is seen in base and isthmus cells of the corpus unit.
TS28: stomach glandular region epithelium peptic cell Present S2C Base , S2C Expression is seen in chief cells.
Specimen S3B - Lgr5: postnatal adult; Pgctm1.1(cre/ERT2)Itoy/Pgc+ (more )
Note: Double labeled: red - Pgc; blue - Lgr5 (assay MGI:7463961).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S3B Lgr5 Isthmus , S3B Lgr5 Base , S3B Lgr5 Expression is seen in gland base and isthmus cells.
TS28: stomach glandular region epithelium peptic cell Present S3B Lgr5 , S3B Lgr5 Base Expression is seen in chief cells.
Specimen S3B - Troy: postnatal adult; Pgctm1.1(cre/ERT2)Itoy/Pgc+ (more )
Note: Double labeled: red - Pgc; blue - Tnfrsf19 (assay MGI:7463964).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S3B Troy Base , S3B Troy Isthmus , S3B Troy Expression is seen in gland base and isthmus cells.
TS28: stomach glandular region epithelium peptic cell Present S3B Troy Base , S3B Troy Expression is seen in chief cells.
Specimen S3B - Mist1: postnatal adult; Pgctm1.1(cre/ERT2)Itoy/Pgc+ (more )
Note: Double labeled: red - Pgc; blue - Bhlha15 (assay MGI:7463958).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S3B Mist1 Isthmus , S3B Mist1 Base , S3B Mist1 Expression is seen in gland base and isthmus cells.
TS28: stomach glandular region epithelium peptic cell Present S3B Mist1 , S3B Mist1 Base Expression is seen in chief cells.
Specimen S3B - Gpr30: postnatal adult; Pgctm1.1(cre/ERT2)Itoy/Pgc+ (more )
Note: Double labeled: red - Pgc; blue - Gper1 (assay MGI:7463960).
Structure Cell Type Level Pattern Image Note
TS28: stomach glandular region gastric gland Present Non-Uniform S3B Gpr30 , S3B Gpr30 Isthmus , S3B Gpr30 Base Expression is seen in gland base and isthmus cells.
TS28: stomach glandular region epithelium peptic cell Present S3B Gpr30 Base , S3B Gpr30 Expression is seen in chief cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory