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Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449018
Gene symbol: Hey2
Gene name: hairy/enhancer-of-split related with YRPW motif 2
Antibody: anti-HEY2 (10597-1-AP)
Detection system: Secondary antibody
Assay notes: Multiple Ggps1 antibodies were described, but the one used in this assay was not detailed. Anti-GGPS1 MGI:7448882 may have been used in this assay.
Results
Specimen 3F E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present Regionally restricted 3F E11.5 Control (left) , 3F E11.5 Control (right) Expression in compact myocardium.
Specimen 3F E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: heart Weak Regionally restricted 3F E11.5 Cre/+ (left) , 3F E11.5 Cre/+ (right) Distribution in compact myocardial nuclei lost.
Specimen 3F E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS20: compact myocardium Present 3F E12.5 Control (left) , 3F E12.5 Control (right)
Specimen 3F E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: heart Weak Regionally restricted 3F E12.5 Cre/+ (left) , 3F E12.5 Cre/+ (right) Distribution in compact myocardial nuclei lost.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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