About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449017
Gene symbol: Myl7
Gene name: myosin, light polypeptide 7, regulatory
Antibody: anti-MYL7 (7283-1-AP)
Detection system: Secondary antibody
Assay notes: Multiple Ggps1 antibodies were described, but the one used in this assay was not detailed. Anti-GGPS1 MGI:7448882 may have been used in this assay.
Results
Specimen S7B E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: myocardium layer Present S7B E10.5 Expression in both trabecular and compact region from E10.5 to E15.5

Specimen S7B E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: myocardium layer Present S7B E11.5 Expression in both trabecular and compact region from E10.5 to E15.5

Specimen S7B E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: compact myocardium Present S7B E12.5 Expression in both trabecular and compact region from E10.5 to E15.5
TS20: trabecular myocardium Present S7B E12.5 Expression in both trabecular and compact region from E10.5 to E15.5

Specimen S7B E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: compact myocardium Present S7B E13.5 Expression in both trabecular and compact region from E10.5 to E15.5
TS21: trabecular myocardium Present S7B E13.5 Expression in both trabecular and compact region from E10.5 to E15.5

Specimen S7B E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: compact myocardium Present S7B E15.5 Expression in both trabecular and compact region from E10.5 to E15.5
TS23: trabecular myocardium Present S7B E15.5 Expression in both trabecular and compact region from E10.5 to E15.5

Specimen S7D E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present S7D E11.5 Control

Specimen S7D E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present S7D E11.5 Cre/+ Expression indistinguishable from control.

Specimen S7D E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present S7D E12.5 Control

Specimen S7D E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present S7D E12.5 Cre/+ Expression indistinguishable from control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory