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Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449013
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: Anti-Ki67 (ab15580)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2F E10.5 Control: embryonic day 10.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+). Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 2F E10.5 Control

Specimen 2F E10.5 Cre/+: embryonic day 10.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present 2F E10.5 Cre/+

Specimen 2F E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+). Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present 2F E11.5 Control

Specimen 2F E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Cell Type Level Pattern Image Note
TS19: cardiac muscle tissue cardiac muscle cell Present 2F E11.5 Cre/+ Number of Ki67-expressing cardiomyocytes not changed compared to control.

Specimen 2F E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+). Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present 2F E11.5 Control

Specimen 2F E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Cell Type Level Pattern Image Note
TS20: cardiac muscle tissue cardiac muscle cell Present 2F E12.5 Cre/+ Number of Ki67-expressing cardiomyocytes not changed compared to control.

Specimen 4G Ki67/cTnT Control: embryonic day 15.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+). Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Level Pattern Image Note
TS23: cardiac muscle tissue Present 4G Ki67/cTnT Control

Specimen 4G Ki67/cTnT Cre/+: embryonic day 15.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant. Double labeled: red - Mki67; green cTnT (Tnnt2 assay MGI:7449011).
Structure Level Pattern Image Note
TS23: cardiac muscle tissue Present 4G pHH3/cTnT Cre/+ No significant difference compared to control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory