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Gene Expression Data
Assay Details
Assay
Reference: J:316204 Chen Z, et al., Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7449008
Gene symbol: Tnnt2
Gene name: troponin T2, cardiac
Antibody: Anti-Troponin T MS295P1 clone 13-11
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2D E10.5 Control: embryonic day 10.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Cell Type Level Pattern Image Note
TS17: cardiac muscle tissue cardiac muscle cell Present 2D E10.5 Control
Specimen 2D E10.5 Cre/+: embryonic day 10.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: cardiac muscle tissue cardiac muscle cell Present 2D E10.5 Cre/+
Specimen 2D E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Cell Type Level Pattern Image Note
TS19: cardiac muscle tissue cardiac muscle cell Present 2D E11.5 Control
Specimen 2D E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: cardiac muscle tissue cardiac muscle cell Weak 2D E11.5 Cre/+ Number of cardiomyocytes reduced at E11.5.
Specimen 2D E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Cell Type Level Pattern Image Note
TS20: cardiac muscle tissue cardiac muscle cell Present 2D E12.5 Control
Specimen 2D E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: cardiac muscle tissue cardiac muscle cell Weak 2D E12.5 Cre/+ Reduction in cardiomyocytes more pronounced by E12.5.
Specimen 5A E10.5 Control: embryonic day 10.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Cell Type Level Pattern Image Note
TS17: cardiac muscle tissue cardiac muscle cell Present 5A E10.5 Control
Specimen 5A E10.5 Cre/+: embryonic day 10.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: cardiac muscle tissue cardiac muscle cell Present 5A E10.5 Cre/+
Specimen 5A E11.5 Control: embryonic day 11.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Cell Type Level Pattern Image Note
TS19: cardiac muscle tissue cardiac muscle cell Present 5A E11.5 Control
Specimen 5A E11.5 Cre/+: embryonic day 11.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS19: cardiac muscle tissue cardiac muscle cell Present Regionally restricted 5A E11.5 Cre/+ Cardiomyocytes in compact zone become round and disorganized after E10.5.
Specimen 5A E12.5 Control: embryonic day 12.5; Ggps1tm1Licj/? (more )
Note: Controls were Cre-negative littermates (fl/fl or fl/+).
Structure Cell Type Level Pattern Image Note
TS20: cardiac muscle tissue cardiac muscle cell Present 5A E12.5 Control
Specimen 5A E12.5 Cre/+: embryonic day 12.5; Ggps1tm1Licj/Ggps1tm1Licj, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: compact myocardium cardiac muscle cell Present Regionally restricted 5A E12.5 Cre/+ Cardiomyocytes in compact zone become round and disorganized after E10.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory