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Gene Expression Data
Assay Details
Assay
Reference: J:202041 Page ME, et al., The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell. 2013 Oct 3;13(4):471-82
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7443206
Gene symbol: Lgr6
Gene name: leucine-rich repeat-containing G protein-coupled receptor 6
Reporter: GFP
Antibody: anti-GFP (ab13970)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1I: postnatal adult; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Back skin in telogen (resting) phase. Double labeled: green - Lgr6; red - Lrig1 (assay MGI:7443158).
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1I Expression is seen in the stem cell niche.
TS28: epidermis Present Scattered 1I Expression in seen in the interfollicular epidermis.
TS28: sebaceous gland Present 1I
TS28: hair follicle isthmus Present 1I
Specimen S1C: postnatal adult; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Back epidermis. Double labeled: green - Lgr6; red - Lrig1 (assay MGI:7443158).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present S1C
Specimen S1D: postnatal adult; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Back epidermis.
Structure Level Pattern Image Note
TS28: epidermis Present Scattered S1D Expression in seen in the interfollicular epidermis.
TS28: sebaceous gland Present S1D
TS28: hair follicle isthmus Present S1D
TS28: hair follicle bulge Present Single cells S1D Expression is seen in the stem cell niche.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory