About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:252121 McCoy AM, et al., IKKbeta Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis. Am J Pathol. 2017 Dec;187(12):2635-2644
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7428906
Gene symbol: Cd68
Gene name: CD68 antigen
Antibody: anti-CD68
Results
Specimen 5A ctrl: embryonic day 17.5; Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Double labeled: green - Cd68; red - phospho-histone H3.
Structure Cell Type Level Pattern Image Note
TS25: lung lung macrophage Present 5A ctrl
Specimen 5A Twist2-IKK: embryonic day 17.5; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: green - Cd68; red - phospho-histone H3.
Structure Cell Type Level Pattern Image Note
TS25: lung lung macrophage Present 5A Twist2-IKK Expression in increased number of macrophages.
Specimen 6C (left) E17 ctrl: embryonic day 17.5; Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Double labeled: green - Cd68; red - Casp1 (assay MGI:7428907).
Structure Cell Type Level Pattern Image Note
TS25: lung lung macrophage Present 6C (left) E17 ctrl
Specimen 6C (left) E17 Twist2-IKK: embryonic day 17.5; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: green - Cd68; red - Casp1 (assay MGI:7428907).
Structure Cell Type Level Pattern Image Note
TS25: lung lung macrophage Present 6C (left) E17 Twist2-IKK
Specimen 6C (left) Adult ctrl: postnatal adult; Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Double labeled: green - Cd68; red - Casp1 (assay MGI:7428907).
Structure Cell Type Level Pattern Image Note
TS28: lung lung macrophage Present 6C (left) Adult ctrl
Specimen 6C (left)) Adult Twist2-IKK: postnatal adult; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: green - Cd68; red - Casp1 (assay MGI:7428907).
Structure Cell Type Level Pattern Image Note
TS28: lung lung macrophage Present 6C (left) Adult Twist2-IKK
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory