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Gene Expression Data
Assay Details
Assay
Reference: J:252121 McCoy AM, et al., IKKbeta Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis. Am J Pathol. 2017 Dec;187(12):2635-2644
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7428905
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-CD31
Results
Specimen 3C ctrl: embryonic day 17.5; Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Double labeled: green - Pecam1; red - Acta2 (assay MGI:7428899).
Structure Cell Type Level Pattern Image Note
TS25: lung lung endothelial cell Present 3C ctrl
Specimen 3C Twist2-IKK: embryonic day 17.5; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Acta2 (assay MGI:7428899).
Structure Cell Type Level Pattern Image Note
TS25: lung lung endothelial cell Strong 3C Twist2-IKK Increased expression in endothelial cells.
Specimen 3E ctrl: embryonic day 17.5; Twist2tm1.1(cre)Dor/Twist2+ (more )
Structure Cell Type Level Pattern Image Note
TS25: lung lung endothelial cell Present 3E ctrl
Specimen 3E Twist2-IKK: embryonic day 17.5; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: lung lung endothelial cell Strong 3E Twist2-IKK Increased expression in endothelial cells.
Specimen 6C (right) E17 ctrl: embryonic day 17.5; Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Double labeled: green - Pecam1; red - Nlrp3 (assay MGI:7428908).
Structure Cell Type Level Pattern Image Note
TS25: lung lung endothelial cell Present 6C (right) E17 ctrl
Specimen 6C (right) E17 Twist2-IKK: embryonic day 17.5; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Nlrp3 (assay MGI:7428908).
Structure Cell Type Level Pattern Image Note
TS25: lung lung endothelial cell Present 6C (right) E17 Twist2-IKK
Specimen 6C (right) Adult ctrl: postnatal adult; Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Double labeled: green - Pecam1; red - Nlrp3 (assay MGI:7428908).
Structure Cell Type Level Pattern Image Note
TS28: lung lung endothelial cell Present 6C (right) Adult ctrl
Specimen 6C (right) Adult Twist2-IKK: postnatal adult; Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Nlrp3 (assay MGI:7428908).
Structure Cell Type Level Pattern Image Note
TS28: lung lung endothelial cell Present 6C (right) Adult Twist2-IKK
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory