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Gene Expression Data
Assay Details
Assay
Reference: J:266596 Kersbergen A, et al., Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427550
Gene symbol: Sftpc
Gene name: surfactant associated protein C
Antibody: anti-proSP-C (AB3786)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Data was quantified in S3B.
Results
Specimen 3I: embryonic day 18.5; Grhl2tm2.1Jane/Grhl2+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 2 cell Present 3I

Specimen 3J: embryonic day 18.5; Grhl2tm1.1Jane/Grhl2tm2.1Jane, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 2 cell Present 3J Dense distribution, but quantification revealed a reduction in the number of positive cells compared with the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory