Grhl2^tm2.1Jane
Targeted Allele Detail

Summary

• Symbol: Grhl2^tm2.1Jane
• Name: grainyhead like transcription factor 2; targeted mutation 1.1, Stephen M Jane
• MGI ID: MGI:7427433
• Gene: Grhl2 Location: Chr15:37233280-37363813 bp, + strand Genetic Position: Chr15, 14.84 cM, cytoband C
• Alliance: Grhl2^tm2.1Jane page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266596
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct flanked exon 2 with loxP sites. Recombination removed the selection cassette. (J:266596)

Expression

In Mice Carrying this Mutation:

52 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grhl2 Mutation: 41 strains or lines available

References

• Original: J:266596 Kersbergen A, et al., Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9
• All: 1 reference(s)